It’s official: Tom Cruise and Penelope Cruz have ended their three-year relationship.

After keeping it hidden for months, Cruise uncovered his sudden split and Access Hollywood knew where he spent Thursday night moments after the announcement.

With the breakup news fresh, Tom managed a smile as he stopped to sign autographs at 1:30 a.m. in the morning outside the Spice Market restaurant in lower Manhattan.

News of the split hit the talk show circuit Friday, surprising Regis Philbin and his special guest host Jay Leno.

“They broke up. Is that right? They got along so good. I’m sorry to hear that. They’re a cute couple. You know when you have the same name it makes it easier,” Leno joked to Regis.

“I’m sorry to hear that. But what can you say about that. They’ll be other loves for the both of them, I’m sure,” said Regis.

Just before the split, Tom flew solo to this year’s Golden Globe awards.

When asked where Penelope was, Tom told Access Hollywood’s Pat O’Brien: “Unfortunately, Penelope had to fly back to Madrid because her father isn’t feeling well.”

People Magazine broke the story of the breakup and Tom’s sister, and new publicist, Lee Anne Devette told us this morning they “broke up at the end of January and it’s amicable. They are incredibly close friends. They care a great deal for each other, they are just not dating anymore.”

Penelope’s spokesperson, Robert Garlock, told Access “they remain good friends and still talk often,” emphasizing “there is no other person involved.”

People Magazine’s Larry Hackett also adds that Tom’s practice of scientology was not a factor in the breakup.

“This is not a religious schism of any kind. They were just two people who were busy. The relationship wasn’t going anywhere,” said Hackett. “Their futures looked the same and I guess they decided it was time to part company.”

The couple, who met on the set of “Vanilla Sky,” while Tom was still married to Nicole Kidman, went public with a photo outside Spago in July 2001. Since then they were a red carpet staple but it started to change late last year.

However, at the couple’s last public appearance in January at “The Last Samurai” premiere in London, Tom said the long-distance factor wasn’t a problem.

“We’re not away from each other that much. There’s moments, a couple weeks here and there,” revealed Tom. “But I have kids and a family… There’s a telephone, fax and it’s really wonderful, actually

*sobs*